Yes. Use Hamlib's k3 driver. Set PTT to RTS (on serial DTR) for best results.
Install pulseaudio-utils and run pasuspender -- ./jtdx to give JTDX exclusive ALSA access. Have you upgraded to JTDX 2.2.160 yet? Share your decode gains and contest scores in the comments below. Until then — clear decodes and 73. Article Word Count: ~1,850 words. Target Keywords: JTDX 2.2.160, JTDX download, JTDX vs WSJT-X, FT8 decoder, weak signal software, ham radio digital modes. jtdx 2.2.160
Not officially, but you can copy the installed folder to a USB drive and run it with --config portable flag. 850 words. Target Keywords: JTDX 2.2.160